Found 16423 results, showing the newest relevant preprints. Sort by relevancy only.Update me on new preprints

Combining Cloud-Based Free Energy Calculations, Synthetically Aware Enumerations and Goal-Directed Generative Machine Learning for Rapid Large-Scale Chemical Exploration and Optimization

We examine the utility of this combined approach by designing potent inhibitors of cyclin-dependent kinase 2 (CDK2) and demonstrate a coupled workflow that can: (1) provide a 6.4 fold enrichment improvement in identifying < 10nM compounds over random selection, and a 1.5 fold enrichment in identifying < 10nM compounds over our previous method (2) rapidly... Expand abstract.
18317 days ago
5/10 relevant
chemRxiv

Stocktaking the environmental coverage of a continental ecosystem observation network

Ausplots outperformed systematic grid, simple random and GRTS in coverage of environmental space (Tukey HSD of mean dispersion, p .001). Expand abstract.
12 hours ago
4/10 relevant
bioRxiv

Advocating for Transgender and Non-Binary Affirmative Spaces in Graduate Education

A table of recommendations and discussion of ways to implement our recommendations are provided. Expand abstract.
17 hours ago
5/10 relevant
PsyArXiv

The Cerebral Cortex Realizes a Universal Probabilistic Model of Computation in Complex Hilbert Spaces

Three well-documented facts are sufficient to define the cortical model of computation: first, cortical dendritic inputs to compute membrane potentials are, in general, complex numbers (amplitudes) that may be configured as state vectors in complex Hilbert spaces; second, normalization is a canonical neural computation, specifically,... Expand abstract.
2 days ago
5/10 relevant
PsyArXiv

Is Aligning Embedding Spaces a Challenging Task? An Analysis of the Existing Methods

This paper provides a theoretical analysis and comparison of the state-of-the-art alignment methods between two embedding spaces representing entity-entity and entity-word. Expand abstract.
3 days ago
6/10 relevant
arXiv

Generalized Kazdan-Warner equations associated with a linear action of a torus on a complex vector space

We introduce generalized Kazdan-Warner equations on Riemannian manifolds associated with a linear action of a torus on a complex vector space. Expand abstract.
3 days ago
6/10 relevant
arXiv

Properties of Set-Valued Stochastic Integrals and Differential Equations with Poisson Jump in a Banach Space

In an M-type 2 Banach space, we explore some properties of set-valued stochastic integrals with respect to Poisson point processes. Expand abstract.
3 days ago
5/10 relevant
arXiv

Disjointness-preserving operators and isospectral Laplacians

All the known counterexamples to Kac' famous question "can one hear the shape of a drum", i.e., does isospectrality of two Laplacians on domains imply that the domains are congruent, consist of pairs of domains composed of copies of isometric building blocks arranged in different ways, such that the unitary operator intertwining the Laplacians acts... Expand abstract.
3 days ago
4/10 relevant
arXiv

Gradual transitivity in orthogonality spaces of finite rank

An orthogonality space is a set together with a symmetric and irreflexive binary relation. Expand abstract.
3 days ago
6/10 relevant
arXiv

Master equation for the finite state space planning problem

We present results of existence, regularity and uniqueness of solutions of the master equation associated with the mean field planning problem in the finite state space case, in the presence of a common noise. Expand abstract.
3 days ago
5/10 relevant
arXiv