Found 587 results, showing the newest relevant preprints. Sort by relevancy only.Update me on new preprints

Reimagining Third Phase Formation as the Miscibility Gap of a Molecular Solution

In analogy to a molecular solution, immediately preceding the liquid-liquid coexistence curve from the single phase region, the metal-ligand complexes percolate. Expand abstract.
117 days ago
5/10 relevant
chemRxiv

Receptor tyrosine kinases regulate signal transduction through a liquid-liquid phase separated state

The inclusion of interacting proteins into liquid-liquid phase-separated (LLPS), membraneless protein droplets maintains functionally relevant proteins at high concentrations in a liquid phase at the required point of action, enhancing equilibrium binding and enzyme activity. Expand abstract.
119 days ago
10/10 relevant
bioRxiv

Extraction on Paper, an Active Learning Technique to Facilitate Student Understanding of Liquid-Liquid Extraction

We envision this activity as a tool to help students understand and apply the chemical principles underlying liquid-liquid extractions outside of and before entering into a laboratory setting. Expand abstract.
126 days ago
10/10 relevant
chemRxiv

Multiphase Complex Coacervate Droplets

Here, we show that the formation of hierarchically organized multiphase droplets with up to three coexisting layers is a generic phenomenon in mixtures of complex coacervates, which serve as models of charge-driven liquid-liquid phase separated systems. Expand abstract.
127 days ago
4/10 relevant
chemRxiv

Granulins modulate liquid-liquid phase separation and aggregation of TDP-43 C-terminal domain

These results constitute the first observation of direct interaction between GRNs and TDP-43 and suggest a mechanism by which the loss of PGRN function could lead to FTLD and ALS. Expand abstract.
127 days ago
8/10 relevant
bioRxiv

Beyond Fermi-Liquid Theory: the $k$-Fermi liquids

We study in this paper the general properties of a many body system of fermions in arbitrary dimensions assuming that the {\em momentum} of individual fermions are good quantum numbers of the system. Expand abstract.
132 days ago
4/10 relevant
arXiv

#ECS236, Tuesday, 15 October 2019, 08:30 - 09:10, Room 209, Molecular Dynamics Analysis on the Behavior of Water and Alcohol Liquids on a OH-Terminated SiO2 Surface

As an equilibrium state, water as well as methanol, ethanol and isopropyl alcohol (IPA) molecules formed a multiple layered structure on the solid surface; however, the microscopic structures were remarkably different between water and IPA liquids because the IPA molecules in the first adsorption layer strongly adsorbed on the solid... Expand abstract.
137 days ago
4/10 relevant
ECSarXiv

Computational insights into mechanism of AIM4-mediated inhibition of aggregation of TDP-43 protein implicated in ALS and evidence for in vitro inhibition of liquid-liquid phase separation (LLPS) of TDP-432C-A315T by AIM4.

We find that AIM4 has a binding site in the C-terminal amyloidogenic core region of amino acids aa: 288-319, which coincides with one of the key residue motifs that could potentially mediate liquid-liquid phase separation (LLPS) of TDP-43. Expand abstract.
140 days ago
10/10 relevant
bioRxiv

ATP-driven separation of liquid phase condensates in bacteria

Liquid-liquid phase separated (LLPS) states are key to compartmentalise components in the absence of membranes, however it is unclear whether LLPS condensates are actively and specifically organized in the sub-cellular space and by which mechanisms. Expand abstract.
145 days ago
5/10 relevant
bioRxiv

Insight into the Mechanisms Driving the Self-Assembly of Functional Interfaces: Moving from Lipids to Charged Amphiphilic Oligomers

In this work we provide new mechanistic insight into the assembly of an amphiphilic polymer-stabilized oil/aqueous interface, in which the headgroups consist of positively charged methylimidazolium ionic liquids, and the tails are short, monodisperse oligodimethylsiloxanes covalently attached to the headgroups. Expand abstract.
146 days ago
4/10 relevant
chemRxiv