Found 1228 results, showing the newest relevant preprints. Sort by relevancy only.Update me on new preprints

An inducible genome editing system for plants

Our tool is easy to construct and will be particularly useful for studying genes which have null-alleles that are non-viable or show strong developmental defects. Expand abstract.
1 hours ago
5/10 relevant
bioRxiv

Evidence of capacitation in the parasitoid wasp, Nasonia vitripennis and its potential role in sex allocation

Genes involved in Cholesterol efflux, a key component of capacitation, along with calcium transport, trypsin and MAPKinase activity were regulated in ovipositing wasps. Expand abstract.
1 hours ago
4/10 relevant
bioRxiv

Combinatorial analysis of Saccharomyces cerevisiae regulatory elements

We find that while enhancers are the initiators of gene activity, core promoters modulate the levels of enhancer mediated expression. Expand abstract.
5 hours ago
4/10 relevant
bioRxiv

A Meta-Analysis of Hippocampal Transcriptional Profiling Studies in a Selectively-Bred Rat Model Provides Converging Evidence with Genetic Sequencing to Implicate Specific Candidate Genes and Pathways in the Liability for Internalizing and Externalizing Psychiatric Disorders

Another functional theme was microglial activation and phagocytosis, including differential expression of pro-inflammatory Complement C1q A chain (C1qa) and the anti-inflammatory Milk fat globule-EGF factor 8 (Mfge8), situated within a chromosomal loci implicated by our concurrent genetic study. Expand abstract.
5 hours ago
5/10 relevant
bioRxiv

Genome-wide association analyses identify variants in IRF4 associated with Acute Myeloid Leukemia and Myelodysplastic Syndrome susceptibility

For each AML and MDS case and control we used PrediXcan to estimate the component of gene expression determined by their genetic profile and correlate this imputed gene expression level with risk of developing disease in a transcriptome-wide association study (TWAS). Expand abstract.
3 days ago
4/10 relevant
bioRxiv

The signal and the noise - characteristics of antisense RNA in complex microbial communities

Studies have successfully used metatranscriptomics to identify and describe relationships between gene expression levels and community characteristics. Expand abstract.
4 days ago
4/10 relevant
bioRxiv

Fabrication of sharp silicon arrays to wound Caenorhabditis elegans

A comparison of the induction of antimicrobial peptide gene expression using traditional needles and the pin arrays demonstrates the utility of this new method. Expand abstract.
4 days ago
4/10 relevant
bioRxiv

5' tRNA halves are highly expressed in the primate hippocampus and sequence-specifically regulate gene expression

We then used a novel k-mer mapping approach to dissect the underlying targeting rules, demonstrating that 5' tRNA halves (5' tRHs) silence genes in a sequence-specific manner, while the most efficient target sites align to the mid-region of the 5' tRH and are located within the CDS or 3' UTR of the target. Expand abstract.
5 days ago
9/10 relevant
bioRxiv

Coordination of transcriptional and translational regulations in human cells infected by Listeria monocytogenes

Pre-silencing the most repressed target gene (PABPC1) slowed down the intracellular multiplication of Listeria, suggesting that the infected host cell can benefit from the repression of genes involved in protein synthesis and thereby better control infection. Expand abstract.
5 days ago
4/10 relevant
bioRxiv