Found 7494 results, showing the newest relevant preprints. Sort by relevancy only.Update me on new preprints

Membrane-Tethered Mucin-like Polypeptides Sterically Inhibit Binding and Slow Fusion Kinetics of Influenza A Virus

Mucins form both a protective barrier that can block virus binding and recruit IAVs to bind cells via the sialic acids of cell-tethered mucins. Expand abstract.
18279 days ago
5/10 relevant
chemRxiv

Investigation of Au SAMs Photoclick Derivatization by PM-IRRAS

Furthermore, to showcase the compatibility of this approach with biochemical applications, cyclopropenone SAMs were irradiated and modified with azide-bearing cell adhesion peptides to promote human fibroblast cell adhesion, then imaged by live cell fluorescence microscopy. Expand abstract.
18279 days ago
4/10 relevant
chemRxiv

A Photoactivable Formaldehyde Donor with Fluorescence Monitoring Reveals Threshold to Arrest Cell Migration

Application of photoFAD-3 uncovered the concentration range necessary for arresting wound healing in live cells. Expand abstract.
18279 days ago
9/10 relevant
chemRxiv

Gibberellin JRA-003: A Selective Inhibitor of Nuclear Translocation of IKKalpha

Not only was JRA-003 (1) identified as the most potent synthetic gibberellin against cancer-derived cell lines, it displayed no cytotoxicity in cells derived from non-cancerous sources (HEK 293T, HS 578BST, HS 888Lu, HS 895Sk, HUVEC). Expand abstract.
18279 days ago
4/10 relevant
chemRxiv

Enzyme-Instructed Assemblies Enable Mitochondria Localization of Histone H2B in Cancer Cells

As the first example of enzyme-instructed self-assembly (EISA) of a synthetic peptide for trafficking endogenous proteins, this work provides insights for understanding and manipulating inter-organelle communication in cells. Expand abstract.
18279 days ago
6/10 relevant
chemRxiv

Comprehensive Survey of CDK Inhibitor Selectivity in Live Cells with Energy Transfer Probes

Here we provide a broadly applicable method for evaluating the selectivity of chemical matter for CDKs in living cells, and present a refined set of tool molecules to study CDK function. Expand abstract.
18279 days ago
9/10 relevant
chemRxiv

Highly Mesoporous Carbon Aerogel as Catalyst Support in Proton Exchange Membrane Fuel Cells

Carbon aerogel possesses unique structural and electrical properties, such as high mesopore volume, specific surface area, and electrical conductivity, which make it suitable for use as a catalyst support in Proton Exchange Membrane Fuel Cells (PEMFC). Expand abstract.
18279 days ago
5/10 relevant
chemRxiv

Stiff-Stilbene Ligands Target G-Quadruplex DNA and Exhibit Selective Anticancer and Antiparasitic Activity

The ligands display selectivity for G4 DNA over duplex DNA and exhibit nanomolar toxicity against Trypasanoma brucei and HeLa cancer cells whist remaining up to two orders of magnitude less toxic to non-tumoral mammalian cell line MRC5. Expand abstract.
18279 days ago
5/10 relevant
chemRxiv

Functionalized NIR-II Semiconducting Polymer Nanoparticles for Single-Cell to Whole-Organ Imaging of PSMA-Positive Prostate Cancer

The targeting mechanism, kinetics, and specificity of BTII-DUPA SPN to PSMA-positive PCa cells are revealed at cellular level with TAM. Expand abstract.
18279 days ago
7/10 relevant
chemRxiv

Interface Engineering by Thiazolium Iodide Passivation Towards Reduced Thermal Diffusion and Performance Improvement in Perovskite Solar Cells

The un-encapsulated perovskite solar cells employing TMI exhibited a remarkable stability under moisture levels (~50% RH) retaining ~95% of initial PCE after 800 h of fabrication, paving potential scalable endeavour. Expand abstract.
18279 days ago
6/10 relevant
chemRxiv